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Alternatively, head back to the guide overview on the getting started page.
In Artemis you can use conditions to make layers and even entire folders hide/display when certain criteria are met.
All conditions are based on something called the data model. This is the place where Artemis stores all the information available to profiles. There is a global data model which is always available (per example: system metrics, current time, active window) and a module-specific data model which contains data limited to the current module (per example: health, ammo, team).
To put it in other words: League of Legends game data is only available in the data model for League of Legends profiles. General info is always available to all profiles.